Sophie von Hellermann lives and works in London. Recent solo exhibitions include Sies + Höke, Düsseldorf (2020); Pilar Corrias, London (2020); Greene Naftali, New York (2019); Parrasch Heijnen Gallery, Los Angeles (2018); Kunstverein Hannover (2017); Vilma Gold, London (2015); Greene Naftali, New York (2013); Firstsite, Colchester, England (2013); and Le Consortium, Dijon (2010). Recent group exhibitions include Greene Naftali, New York (2021); Bonner Kunstverein, Bonn (2016); Gallery Met, Metropolitan Opera, New York (2014); and Cranford Collection, Fundación Banco Santander, Madrid (2013).

Her work is in the collections of the Los Angeles Country Museum of Art and The Metropolitan Museum of Art, New York, among others. Von Hellermann is a founding member of the London and Düsseldorf-based artists collective hobbypopMUSEUM, active since 2006.